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BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
BIBM
2008
IEEE
108views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Systematic Evaluation of Scaling Methods for Gene Expression Data
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
Gaurav Pandey, Lakshmi Naarayanan Ramakrishnan, Mi...
BIBM
2008
IEEE
113views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Towards Site-Based Protein Functional Annotations
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
Seak Fei Lei, Jun Huan
CEC
2008
IEEE
14 years 3 months ago
The simplest evolution/learning hybrid: LEM with KNN
Abstract— The Learnable Evolution Model (LEM) was introduced by Michalski in 2000, and involves interleaved bouts of evolution and learning. Here we investigate LEM in (we think)...
Guleng Sheri, David W. Corne
CEC
2008
IEEE
14 years 3 months ago
Auto-tuning fuzzy granulation for evolutionary optimization
—Much of the computational complexity in employing evolutionary algorithms as optimization tool is due to the fitness function evaluation that may either not exist or be computat...
Mohsen Davarynejad, Mohammad R. Akbarzadeh-Totonch...