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AIEDAM
2008
114views more  AIEDAM 2008»
13 years 9 months ago
Design rationale: Researching under uncertainty
Rationale research in software development is a challenging area because while there is no shortage of advocates for its value, there is also no shortage of reasons for why rationa...
Janet E. Burge
BIODATAMINING
2008
178views more  BIODATAMINING 2008»
13 years 9 months ago
Clustering-based approaches to SAGE data mining
Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Haiying Wang, Huiru Zheng, Francisco Azuaje
BIODATAMINING
2008
147views more  BIODATAMINING 2008»
13 years 9 months ago
Neural networks for genetic epidemiology: past, present, and future
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...
Alison A. Motsinger-Reif, Marylyn D. Ritchie
BMCBI
2008
87views more  BMCBI 2008»
13 years 9 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2008
122views more  BMCBI 2008»
13 years 9 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood