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BMCBI
2010
142views more  BMCBI 2010»
13 years 7 months ago
Classification of protein sequences by means of irredundant patterns
Background: The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of diff...
Matteo Comin, Davide Verzotto
BMCBI
2006
159views more  BMCBI 2006»
13 years 7 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2006
124views more  BMCBI 2006»
13 years 7 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
BMCBI
2004
167views more  BMCBI 2004»
13 years 7 months ago
Feature selection for splice site prediction: A new method using EDA-based feature ranking
Background: The identification of relevant biological features in large and complex datasets is an important step towards gaining insight in the processes underlying the data. Oth...
Yvan Saeys, Sven Degroeve, Dirk Aeyels, Pierre Rou...
RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael