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ISMB
1997
13 years 8 months ago
Inferring Gene Structures in Genomic Sequences Using Pattern Recognition and Expressed Sequence Tags
Abstract.) Ying Xu, Richard J. MuraF, and Edward C. Uberbacher Computer Science and Mathematics Division and tLife Sciences Division Computational methods for gene identification ...
Ying Xu, Richard J. Mural, Edward C. Uberbacher
CSB
2005
IEEE
168views Bioinformatics» more  CSB 2005»
14 years 1 months ago
cis-Regulatory Element Prediction in Mammalian Genomes
The identification of cis-regulatory elements and modules is an important step in understanding the regulation of genes. We have developed a pipeline capable of running multiple m...
Asim S. Siddiqui, Gordon Robertson, Misha Bilenky,...
BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan