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» Identifying Binding Sites in Sequential Genomic Data
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BMCBI
2007
136views more  BMCBI 2007»
13 years 8 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
BMCBI
2008
134views more  BMCBI 2008»
13 years 8 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
BMCBI
2008
169views more  BMCBI 2008»
13 years 8 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
NIPS
2008
13 years 10 months ago
Predicting the Geometry of Metal Binding Sites from Protein Sequence
Metal binding is important for the structural and functional characterization of proteins. Previous prediction efforts have only focused on bonding state, i.e. deciding which prot...
Paolo Frasconi, Andrea Passerini