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BMCBI
2010
122views more  BMCBI 2010»
13 years 2 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
BMCBI
2008
166views more  BMCBI 2008»
13 years 7 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
GECCO
2006
Springer
202views Optimization» more  GECCO 2006»
13 years 11 months ago
Inference of genetic networks using S-system: information criteria for model selection
In this paper we present an evolutionary approach for inferring the structure and dynamics in gene circuits from observed expression kinetics. For representing the regulatory inte...
Nasimul Noman, Hitoshi Iba
BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...