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BMCBI
2004
115views more  BMCBI 2004»
13 years 8 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
ICPPW
2009
IEEE
13 years 6 months ago
A Scalable Parallel Approach for Peptide Identification from Large-Scale Mass Spectrometry Data
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Gaurav Ramesh Kulkarni, Ananth Kalyanaraman, Willi...
ASPLOS
2012
ACM
12 years 4 months ago
Relyzer: exploiting application-level fault equivalence to analyze application resiliency to transient faults
Future microprocessors need low-cost solutions for reliable operation in the presence of failure-prone devices. A promising approach is to detect hardware faults by deploying low-...
Siva Kumar Sastry Hari, Sarita V. Adve, Helia Naei...
BMCBI
2006
123views more  BMCBI 2006»
13 years 8 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
BMCBI
2006
123views more  BMCBI 2006»
13 years 8 months ago
How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different result
Background: Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of the Mic...
Frank F. Millenaar, John Okyere, Sean T. May, Mart...