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» Identifying Protein Flexibility by NMA
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BIBE
2008
IEEE
14 years 1 months ago
VIP: Visualization of integrated proteomics data
—The post-genomic era is characterized by the rapid data accumulation leading to unwieldy and large volumes of biological data. The proteomics results (large sets of identified p...
Eugenia G. Giannopoulou, Giorgos Lepouras, Elias S...
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2006
180views more  BMCBI 2006»
13 years 7 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2006
84views more  BMCBI 2006»
13 years 7 months ago
Representation of target-bound drugs by computed conformers: implications for conformational libraries
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
Stefan Günther, Christian Senger, Elke Michal...
BMCBI
2010
146views more  BMCBI 2010»
13 years 7 months ago
Booly: a new data integration platform
Background: Data integration is an escalating problem in bioinformatics. We have developed a web tool and warehousing system, Booly, that features a simple yet flexible data model...
Long H. Do, Francisco F. Esteves, Harvey J. Karten...