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» Identifying Structural Motifs in Proteins
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ISMB
1998
13 years 11 months ago
Modeling Protein Homopolymeric Repeats: Possible Polyglutamine Structural Motifs for Huntington's Disease
Wedescribe a prototype system (Poly-X) for assisting an expert user in modelingprotein repeats. Poly-X reduces the large numberof degrees of freedomrequired to specify a protein m...
Richard H. Lathrop, Malcolm S. Casale, Douglas J. ...
BMCBI
2004
77views more  BMCBI 2004»
13 years 9 months ago
A structural study for the optimisation of functional motifs encoded in protein sequences
Background: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that
Allegra Via, Manuela Helmer-Citterich
BIOINFORMATICS
2010
98views more  BIOINFORMATICS 2010»
13 years 7 months ago
Characterizing the regularity of tetrahedral packing motifs in protein tertiary structure
Ryan Day, Kristin P. Lennox, David B. Dahl, Marina...
BMCBI
2010
123views more  BMCBI 2010»
13 years 4 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
NAR
1998
161views more  NAR 1998»
13 years 9 months ago
Touring protein fold space with Dali/FSSP
The FSSP database and its new supplement, the Dali Domain Dictionary, present a continuously updated classification of all known 3D protein structures. The classification is deriv...
Liisa Holm, Chris Sander