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» Identifying Structural Motifs in Proteins
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BMCBI
2005
108views more  BMCBI 2005»
13 years 9 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
CCECE
2006
IEEE
14 years 3 months ago
Evaluation of RNA Secondary Structure Motifs using Regression Analysis
Recent experimental evidences have shown that ribonucleic acid (RNA) plays a greater role in the cell than previously thought. An ensemble of RNA sequences believed to contain sig...
Mohammad Anwar, Marcel Turcotte
ICML
2005
IEEE
14 years 10 months ago
Predicting protein folds with structural repeats using a chain graph model
Protein fold recognition is a key step towards inferring the tertiary structures from amino-acid sequences. Complex folds such as those consisting of interacting structural repeat...
Yan Liu, Eric P. Xing, Jaime G. Carbonell
ISMB
1998
13 years 11 months ago
Bayesian Protein Family Classifier
A Bayesian procedure for the simultaneous alignment and classification of sequences into subclasses is described. This Gibbs sampling algorithm iterates between an alignment step ...
Kunbin Qu, Lee Ann McCue, Charles E. Lawrence
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
14 years 3 months ago
Graph Alignments: A New Concept to Detect Conserved Regions in Protein Active Sites
: We introduce the novel concept of graph alignment, a generalization of graph isomorphism that is motivated by the commonly used multiple sequence alignments. Graph alignments and...
Nils Weskamp, Eyke Hüllermeier, Daniel Kuhn, ...