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» Identifying Structural Motifs in Proteins
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ADC
2006
Springer
158views Database» more  ADC 2006»
14 years 3 months ago
Dimensionality reduction in patch-signature based protein structure matching
Searching bio-chemical structures is becoming an important application domain of information retrieval. This paper introduces a protein structure matching problem and formulates i...
Zi Huang, Xiaofang Zhou, Dawei Song, Peter Bruza
RECOMB
2005
Springer
14 years 10 months ago
Segmentation Conditional Random Fields (SCRFs): A New Approach for Protein Fold Recognition
Abstract. Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e. segmenta...
Yan Liu, Jaime G. Carbonell, Peter Weigele, Vanath...
BMCBI
2006
137views more  BMCBI 2006»
13 years 10 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
BMCBI
2005
106views more  BMCBI 2005»
13 years 9 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
BMCBI
2004
207views more  BMCBI 2004»
13 years 9 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...