Sciweavers

428 search results - page 70 / 86
» Identifying Structural Motifs in Proteins
Sort
View
BMCBI
2006
100views more  BMCBI 2006»
13 years 10 months ago
STAR: predicting recombination sites from amino acid sequence
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
Denis C. Bauer, Mikael Bodén, Ricarda Thier...
BMCBI
2006
127views more  BMCBI 2006»
13 years 10 months ago
Exploring supervised and unsupervised methods to detect topics in biomedical text
Background: Topic detection is a task that automatically identifies topics (e.g., "biochemistry" and "protein structure") in scientific articles based on infor...
Minsuk Lee, Weiqing Wang, Hong Yu
BMCBI
2008
84views more  BMCBI 2008»
13 years 10 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2010
191views more  BMCBI 2010»
13 years 5 months ago
Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
Background: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rath...
Soja Saghar Soman, Krishnankutty Chandrika Sivakum...
BMCBI
2006
118views more  BMCBI 2006»
13 years 10 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...