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» Identifying Structural Motifs in Proteins
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NAR
2007
130views more  NAR 2007»
13 years 9 months ago
The SLiMDisc server: short, linear motif discovery in proteins
Short, linear motifs (SLiMs) play a critical role in many biological processes, particularly in protein–protein interactions. Overrepresentation of convergent occurrences of mot...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
SSDBM
2007
IEEE
131views Database» more  SSDBM 2007»
14 years 4 months ago
Mining RNA Tertiary Motifs with Structure Graphs
We present a novel application of graph database mining to identify tertiary motifs in RNA structures. In od, we abstract an RNA molecule as a labeled graph and use a frequent sub...
Xueyi Wang, Jun Huan, Jack Snoeyink, Wei Wang 0010
NAR
2008
119views more  NAR 2008»
13 years 9 months ago
MALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, ...
Hua Cheng, Bong-Hyun Kim, Nick V. Grishin
BIRD
2007
Springer
107views Bioinformatics» more  BIRD 2007»
14 years 4 months ago
Prediction of Structurally-Determined Coiled-Coil Domains with Hidden Markov Models
The coiled-coil protein domain is a widespread structural motif known to be involved in a wealth of key interactions in cells and organisms. Coiled-coil recognition and prediction ...
Piero Fariselli, Daniele Molinini, Rita Casadio, A...
BMCBI
2007
115views more  BMCBI 2007»
13 years 9 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...