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BMCBI
2008
108views more  BMCBI 2008»
13 years 6 months ago
Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
Sacha A. F. T. van Hijum, Richard J. S. Baerends, ...
BMCBI
2008
140views more  BMCBI 2008»
13 years 6 months ago
Corpus annotation for mining biomedical events from literature
Background: Advanced Text Mining (TM) such as semantic enrichment of papers, event or relation extraction, and intelligent Question Answering have increasingly attracted attention...
Jin-Dong Kim, Tomoko Ohta, Jun-ichi Tsujii
BMCBI
2008
121views more  BMCBI 2008»
13 years 6 months ago
ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
BMCBI
2008
79views more  BMCBI 2008»
13 years 6 months ago
In silico docking of urokinase plasminogen activator and integrins
Background: Urokinase, its receptor and the integrins are functionally associated and involved in regulation of cell signaling, migration, adhesion and proliferation. No structura...
Bernard Degryse, Juan Fernández-Recio, Vale...
BMCBI
2008
100views more  BMCBI 2008»
13 years 6 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...