Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
Ivan Borozan, Limin Chen, Bryan Paeper, Jenny E. H...
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...