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BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...
ICCS
2005
Springer
14 years 1 months ago
Querying a Bioinformatic Data Sources Registry with Concept Lattices
Abstract Bioinformatic data sources available on the web are multiple and heterogenous. The lack of documentation and the difficulty of interaction with these data banks require us...
Nizar Messai, Marie-Dominique Devignes, Amedeo Nap...
BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2005
112views more  BMCBI 2005»
13 years 7 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...