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RECOMB
2005
Springer
14 years 8 months ago
The Incompatible Desiderata of Gene Cluster Properties
Abstract. There is widespread interest in comparative genomics in determining if historically and/or functionally related genes are spatially clustered in the genome, and whether t...
Rose Hoberman, Dannie Durand
ALMOB
2008
160views more  ALMOB 2008»
13 years 8 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
BMCBI
2006
97views more  BMCBI 2006»
13 years 8 months ago
REEF: searching REgionally Enriched Features in genomes
Background: In Eukaryotic genomes, different features including genes are not uniformly distributed. The integration of annotation information and genomic position of functional D...
Alessandro Coppe, Gian Antonio Danieli, Stefania B...
BMCBI
2008
187views more  BMCBI 2008»
13 years 8 months ago
PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
BMCBI
2010
96views more  BMCBI 2010»
13 years 8 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart