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BMCBI
2010
101views more  BMCBI 2010»
13 years 8 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
CSB
2004
IEEE
103views Bioinformatics» more  CSB 2004»
14 years 9 days ago
Identifying MicroRNAs in Plant Genomes
The ability to control gene expression during development in plants could be used for improving crop yields, resistance to disease, and environmental adaptability. It has been sug...
Christopher Maher, Marja Timmermans, Lincoln Stein...
BMCBI
2011
13 years 4 days ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
BIBE
2007
IEEE
121views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
Identifying Genomic Regulators of Set-Wise Co-Expression
The genetical genomics approach has been used to study the genetic basis of variation in gene expression, where putative transcriptional regulators of genes are identified via gene...
Jung Hoon Woo, Tian Zheng, Ju Han Kim
BMCBI
2004
117views more  BMCBI 2004»
13 years 8 months ago
CisOrtho: A program pipeline for genome-wide identification of transcription factor target genes using phylogenetic footprinting
Background: All known genomes code for a large number of transcription factors. It is important to develop methods that will reveal how these transcription factors act on a genome...
Henry R. Bigelow, Adam S. Wenick, Allan Wong, Oliv...