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BC
2010
163views more  BC 2010»
13 years 6 months ago
Action and behavior: a free-energy formulation
We have previously tried to explain perceptual inference and learning under a free-energy principle that pursues Helmholtz's agenda to understand the brain in terms of energy ...
Karl J. Friston, Jean Daunizeau, James Kilner, Ste...
BMCBI
2010
126views more  BMCBI 2010»
13 years 6 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
BMCBI
2010
176views more  BMCBI 2010»
13 years 6 months ago
Haplotype association analyses in resources of mixed structure using Monte Carlo testing
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
Ryan Abo, Jathine Wong, Alun Thomas, Nicola J. Cam...
BMCBI
2010
121views more  BMCBI 2010»
13 years 6 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
BMCBI
2010
97views more  BMCBI 2010»
13 years 6 months ago
Preprocessing of gene expression data by optimally robust estimators
Background: The preprocessing of gene expression data obtained from several platforms routinely includes the aggregation of multiple raw signal intensities to one expression value...
Matthias Kohl, Hans-Peter Deigner
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