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BMCBI
2011
13 years 18 days ago
FIND: A new software tool and development platform for enhanced multicolor flow analysis
Background: Flow Cytometry is a process by which cells, and other microscopic particles, can be identified, counted, and sorted mechanically through the use of hydrodynamic pressu...
Shareef Dabdoub, William C. Ray, Sheryl S. Justice
BMCBI
2011
13 years 18 days ago
Efficient alignment of pyrosequencing reads for re-sequencing applications
Background: Over the past few years, new massively parallel DNA sequencing technologies have emerged. These platforms generate massive amounts of data per run, greatly reducing th...
Francisco Fernandes, Paulo G. S. da Fonseca, Lu&ia...
BMCBI
2011
13 years 18 days ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
BMCBI
2011
13 years 18 days ago
Genotype calling in tetraploid species from bi-allelic marker data using mixture models
Background: Automated genotype calling in tetraploid species was until recently not possible, which hampered genetic analysis. Modern genotyping assays often produce two signals, ...
Roeland E. Voorrips, Gerrit Gort, Ben Vosman
BMCBI
2011
13 years 18 days ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes
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