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BMCBI
2010
13 years 7 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
BMCBI
2008
13 years 7 months ago
2008
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
BMCBI
2010
13 years 7 months ago
2010
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
BMCBI
2008
13 years 7 months ago
2008
Background: Microarray technology provides an efficient means for globally exploring physiological processes governed by the coordinated expression of multiple genes. However, ide...
BMCBI
2006
13 years 7 months ago
2006
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...