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UAI
2003
15 years 5 months ago
On the Convergence of Bound Optimization Algorithms
Many practitioners who use EM and related algorithms complain that they are sometimes slow. When does this happen, and what can be done about it? In this paper, we study the gener...
Ruslan Salakhutdinov, Sam T. Roweis, Zoubin Ghahra...
ALMOB
2007
155views more  ALMOB 2007»
15 years 4 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
BMCBI
2010
152views more  BMCBI 2010»
15 years 4 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
CORR
2008
Springer
103views Education» more  CORR 2008»
15 years 4 months ago
Quickest Change Detection of a Markov Process Across a Sensor Array
Recent attention in quickest change detection in the multi-sensor setting has been on the case where the densities of the observations change at the same instant at all the sensor...
Vasanthan Raghavan, Venugopal V. Veeravalli
MANSCI
2007
102views more  MANSCI 2007»
15 years 3 months ago
Implications of Renegotiation for Optimal Contract Flexibility and Investment
After entering into supply contracts, firms often later renegotiate the terms of those contracts. For example, firms that obtain market demand information after signing supply c...
Erica L. Plambeck, Terry A. Taylor