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118
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BMCBI
2010
131views more  BMCBI 2010»
15 years 2 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
128
Voted
BMCBI
2010
101views more  BMCBI 2010»
15 years 2 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
125
Voted
BMCBI
2010
152views more  BMCBI 2010»
15 years 2 months ago
Apples and oranges: avoiding different priors in Bayesian DNA sequence analysis
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
BMCBI
2010
81views more  BMCBI 2010»
15 years 2 months ago
Discrete wavelet transform de-noising in eukaryotic gene splicing
Background: This paper compares the most common digital signal processing methods of exon prediction in eukaryotes, and also proposes a technique for noise suppression in exon pre...
Tina P. George, Tessamma Thomas
107
Voted
BMCBI
2010
119views more  BMCBI 2010»
15 years 2 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
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