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BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2006
155views more  BMCBI 2006»
13 years 10 months ago
Analysis of promoter regions of co-expressed genes identified by microarray analysis
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
Srinivas Veerla, Mattias Höglund
BMCBI
2006
130views more  BMCBI 2006»
13 years 10 months ago
Spatial normalization of array-CGH data
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
Pierre Neuvial, Philippe Hupé, Isabel Brito...
BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
CAD
2006
Springer
13 years 10 months ago
An efficient, error-bounded approximation algorithm for simulating quasi-statics of complex linkages
Design and analysis of articulated mechanical structures, commonly referred to as linkages, is an integral part of any CAD/CAM system. The most common approaches formulate the pro...
Stephane Redon, Ming C. Lin
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