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APBC
2004
116views Bioinformatics» more  APBC 2004»
13 years 9 months ago
Structure-Function Relationship in DNA Sequence Recognition by Transcription Factors
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
Akinori Sarai, Samuel Selvaraj, M. Michael Gromiha...
ICARIS
2010
Springer
13 years 9 months ago
Defining a Simulation Strategy for Cancer Immunocompetence
Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. R...
Grazziela P. Figueredo, Uwe Aickelin
BMCBI
2007
146views more  BMCBI 2007»
13 years 8 months ago
Spatial location and its relevance for terminological inferences in bio-ontologies
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
Stefan Schulz, Kornél G. Markó, Udo ...
BMCBI
2006
82views more  BMCBI 2006»
13 years 8 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
CSCW
2002
ACM
13 years 7 months ago
NetWORKers and their Activity in Intensional Networks
Through ethnographic research, we document the rise of personal social networks in the workplace, which we call intensional networks. Paradoxically, we find that the most fundament...
Bonnie A. Nardi, Steve Whittaker, Heinrich Schwarz