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BMCBI
2006
139views more  BMCBI 2006»
13 years 6 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
BMCBI
2006
130views more  BMCBI 2006»
13 years 6 months ago
CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
Kevin A. Greer, Matthew R. McReynolds, Heddwen L. ...
BMCBI
2011
13 years 1 months ago
Using Stochastic Causal Trees to Augment Bayesian Networks for Modeling eQTL Datasets
Background: The combination of genotypic and genome-wide expression data arising from segregating populations offers an unprecedented opportunity to model and dissect complex phen...
Kyle C. Chipman, Ambuj K. Singh
BMCBI
2005
142views more  BMCBI 2005»
13 years 6 months ago
CLU: A new algorithm for EST clustering
Background: The continuous flow of EST data remains one of the richest sources for discoveries in modern biology. The first step in EST data mining is usually associated with EST ...
Andrey A. Ptitsyn, Winston Hide
BMCBI
2010
135views more  BMCBI 2010»
13 years 6 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...