The improvement on the QSAR prediction of the trans-stilbenes affinity for the -amyloid peptide (employed for detecting the Alzheimer disease) achieved by means of using approximat...
Irene Luque Ruiz, Manuel Urbano-Cuadrado, Miguel &...
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
Machine Learning techniques are successfully applied to establish quantitative relations between chemical structure and biological activity (QSAR), i.e. classify compounds as activ...
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Planning in partially-observable dynamical systems is a challenging problem, and recent developments in point-based techniques such as Perseus significantly improve performance as...