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BMCBI
2010
106views more  BMCBI 2010»
13 years 8 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
CSDA
2008
128views more  CSDA 2008»
13 years 8 months ago
Classification tree analysis using TARGET
Tree models are valuable tools for predictive modeling and data mining. Traditional tree-growing methodologies such as CART are known to suffer from problems including greediness,...
J. Brian Gray, Guangzhe Fan
PR
2006
141views more  PR 2006»
13 years 7 months ago
Relaxational metric adaptation and its application to semi-supervised clustering and content-based image retrieval
The performance of many supervised and unsupervised learning algorithms is very sensitive to the choice of an appropriate distance metric. Previous work in metric learning and ada...
Hong Chang, Dit-Yan Yeung, William K. Cheung
TCBB
2011
13 years 2 months ago
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
Zengyou He, Can Yang, Weichuan Yu