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147
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BMCBI
2010
15 years 4 months ago
2010
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
146
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BMCBI
2008
15 years 4 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
143
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BMCBI
2008
15 years 4 months ago
2008
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
139
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BMCBI
2010
15 years 4 months ago
2010
Background: Mass spectrometry (MS) coupled with online separation methods is commonly applied for differential and quantitative profiling of biological samples in metabolomic as w...
144
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BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
15 years 4 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...