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BMCBI
2006
148views more  BMCBI 2006»
15 years 4 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
BMCBI
2006
153views more  BMCBI 2006»
15 years 4 months ago
Automatic document classification of biological literature
Background: Document classification is a wide-spread problem with many applications, from organizing search engine snippets to spam filtering. We previously described Textpresso, ...
David Chen, Hans-Michael Müller, Paul W. Ster...
BMCBI
2006
116views more  BMCBI 2006»
15 years 4 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
93views more  BMCBI 2006»
15 years 4 months ago
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
Simon Katz, Rafael A. Irizarry, Xue Lin, Mark Trip...
BMCBI
2006
112views more  BMCBI 2006»
15 years 4 months ago
Distill: a suite of web servers for the prediction of one-, two- and three-dimensional structural features of proteins
Background: We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbo...
Davide Baù, Alberto J. M. Martin, Catherine...
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