Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Log-linear parsing models are often trained by optimizing likelihood, but we would prefer to optimise for a task-specific metric like Fmeasure. Softmax-margin is a convex objecti...
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Textual CBR systems solve problems by reusing experiences that are in textual form. Knowledge-rich comparison of textual cases remains an important challenge for these systems. How...