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» Including Biological Literature Improves Homology Search
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2008
Springer
13 years 10 months ago
Reactive Stochastic Local Search Algorithms for the Genomic Median Problem
Abstract. The genomic median problem is an optimization problem inspired by a biological issue: it aims at finding the chromosome organization of the common ancestor to multiple li...
Renaud Lenne, Christine Solnon, Thomas Stützl...
BMCBI
2005
100views more  BMCBI 2005»
13 years 8 months ago
Evolutionary models for insertions and deletions in a probabilistic modeling framework
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
Elena Rivas
BMCBI
2005
132views more  BMCBI 2005»
13 years 8 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
PPLook: an automated data mining tool for protein-protein interaction
Background: Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of inter...
Shao-Wu Zhang, Yao-Jun Li, Li Xia, Quan Pan
BMCBI
2010
196views more  BMCBI 2010»
13 years 6 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...