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BMCBI
2010
124views more  BMCBI 2010»
13 years 8 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
ICDM
2002
IEEE
158views Data Mining» more  ICDM 2002»
14 years 29 days ago
Adaptive dimension reduction for clustering high dimensional data
It is well-known that for high dimensional data clustering, standard algorithms such as EM and the K-means are often trapped in local minimum. Many initialization methods were pro...
Chris H. Q. Ding, Xiaofeng He, Hongyuan Zha, Horst...
CGF
2008
142views more  CGF 2008»
13 years 8 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
BMCBI
2008
158views more  BMCBI 2008»
13 years 8 months ago
Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent compo
Background: The analysis of high-throughput gene expression data sets derived from microarray experiments still is a field of extensive investigation. Although new approaches and ...
Dominik Lutter, Peter Ugocsai, Margot Grandl, Evel...
BIOSYSTEMS
2008
75views more  BIOSYSTEMS 2008»
13 years 8 months ago
Using matrix of thresholding partial correlation coefficients to infer regulatory network
DNA arrays measure the expression levels for thousands of genes simultaneously under different conditions. These measurements reflect many aspects of the underlying biological pro...
Lide Han, Jun Zhu