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BMCBI
2008
152views more  BMCBI 2008»
13 years 9 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...
BMCBI
2008
84views more  BMCBI 2008»
13 years 9 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2008
121views more  BMCBI 2008»
13 years 9 months ago
ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
BMCBI
2008
133views more  BMCBI 2008»
13 years 9 months ago
Towards ontology-driven navigation of the lipid bibliosphere
Background: The indexing of scientific literature and content is a relevant and contemporary requirement within life science information systems. Navigating information available ...
Christopher J. O. Baker, Kanagasabai Rajaraman, We...
CORR
2010
Springer
188views Education» more  CORR 2010»
13 years 9 months ago
A physically-based particle model of emergent crowd behaviors
This paper presents a modeling process in order to produce a realistic simulation of crowds in the ancient Greek agora of Argos. This place was a social theater in which two kinds...
Laure Heïgéas, Annie Luciani, Joë...