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PROCEDIA
2010
84views more  PROCEDIA 2010»
13 years 9 months ago
Individual-based simulation of sexual selection: A quantitative genetic approach
Sexual selection has been mathematically modeled using quantitative genetics as well as population genetics. Two-locus simulation models have been used to study the evolution of m...
D. van Dijk, Peter M. A. Sloot, J. C. Tay, M. C. S...
BMCBI
2010
124views more  BMCBI 2010»
13 years 11 months ago
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
Elena E. Giorgi, Bob Funkhouser, Gayathri Athreya,...
BMCBI
2006
142views more  BMCBI 2006»
13 years 11 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
BMCBI
2008
186views more  BMCBI 2008»
13 years 11 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2005
201views more  BMCBI 2005»
13 years 10 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota