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BMCBI
2010
128views more  BMCBI 2010»
13 years 10 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro
BMCBI
2008
126views more  BMCBI 2008»
13 years 10 months ago
FCI: an R-based algorithm for evaluating uncertainty of absolute real-time PCR quantification
Background: FCI is an R code for analyzing data from real-time PCR experiments. This algorithm estimates standard curve features as well as nucleic acid concentrations and confide...
Paolo Verderio, Sara Pizzamiglio, Fabio Gallo, Sim...
BMCBI
2006
85views more  BMCBI 2006»
13 years 10 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
JSA
2008
108views more  JSA 2008»
13 years 10 months ago
A methodology to design arbitrary failure detectors for distributed protocols
Nowadays, there are many protocols able to cope with process crashes, but, unfortunately, a process crash represents only a particular faulty behavior. Handling tougher failures (...
Roberto Baldoni, Jean-Michel Hélary, Sara T...
BMCBI
2005
97views more  BMCBI 2005»
13 years 10 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles