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JBCB
2007
161views more  JBCB 2007»
13 years 7 months ago
On Cooperative Quasi-Equilibrium Models of transcriptional Regulation
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...
Eric Mjolsness
HIPC
2009
Springer
13 years 5 months ago
Comparing the performance of clusters, Hadoop, and Active Disks on microarray correlation computations
Abstract--Microarray-based comparative genomic hybridization (aCGH) offers an increasingly fine-grained method for detecting copy number variations in DNA. These copy number variat...
Jeffrey A. Delmerico, Nathanial A. Byrnes, Andrew ...
BMCBI
2010
155views more  BMCBI 2010»
13 years 7 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
SIGMOD
2008
ACM
215views Database» more  SIGMOD 2008»
14 years 7 months ago
CSV: visualizing and mining cohesive subgraphs
Extracting dense sub-components from graphs efficiently is an important objective in a wide range of application domains ranging from social network analysis to biological network...
Nan Wang, Srinivasan Parthasarathy, Kian-Lee Tan, ...
BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...