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LPNMR
2005
Springer
14 years 25 days ago
Inference of Gene Relations from Microarray Data by Abduction
We describe an application of Abductive Logic Programming (ALP) to the analysis of an important class of DNA microarray experiments. We develop an ALP theory that provides a simple...
Irene Papatheodorou, Antonis C. Kakas, Marek J. Se...
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi
BMCBI
2006
203views more  BMCBI 2006»
13 years 7 months ago
Genome-wide prediction of transcriptional regulatory elements of human promoters using gene expression and promoter analysis dat
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
Seon-Young Kim, YongSung Kim
EMO
2005
Springer
108views Optimization» more  EMO 2005»
14 years 27 days ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...