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BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2010
167views more  BMCBI 2010»
13 years 7 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
CCE
2005
13 years 7 months ago
Large-scale inference of the transcriptional regulation of Bacillus subtilis
This paper addresses the inference of the transcriptional regulatory network of Bacillus subtilis. Two inference approaches, a linear, additive model and a non-linear power-law mo...
Anshuman Gupta, Jeffrey D. Varner, Costas D. Maran...
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 25 days ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
CIARP
2009
Springer
14 years 2 months ago
Analysis of the GRNs Inference by Using Tsallis Entropy and a Feature Selection Approach
Abstract. An important problem in the bioinformatics field is to understand how genes are regulated and interact through gene networks. This knowledge can be helpful for many appl...
Fabrício Martins Lopes, Evaldo A. de Olivei...