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BMCBI
2010
165views more  BMCBI 2010»
13 years 8 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2005
88views more  BMCBI 2005»
13 years 8 months ago
Using large-scale perturbations in gene network reconstruction
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computatio...
Thomas MacCarthy, Andrew Pomiankowski, Robert Seym...
BMCBI
2006
239views more  BMCBI 2006»
13 years 8 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2010
118views more  BMCBI 2010»
13 years 8 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
AAAI
2007
13 years 11 months ago
Biomind ArrayGenius and GeneGenius: Web Services Offering Microarray and SNP Data Analysis via Novel Machine Learning Methods
Analysis of postgenomic biological data (such as microarray and SNP data) is a subtle art and science, and the statistical methods most commonly utilized sometimes prove inadequat...
Ben Goertzel, Cassio Pennachin, Lúcio de So...