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BIOINFORMATICS
2005
134views more  BIOINFORMATICS 2005»
13 years 8 months ago
Outcome signature genes in breast cancer: is there a unique set?
Motivation: direct bearing whose expres Sorlie et al., 2 gene sets is a diseases (Lossos et al., 2004; Miklos and Maleszka, 2004), and the variables that could account questions i...
Liat Ein-Dor, Itai Kela, Gad Getz, David Givol, Ey...
BMCBI
2004
117views more  BMCBI 2004»
13 years 8 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2010
121views more  BMCBI 2010»
13 years 3 months ago
G-stack modulated probe intensities on expression arrays - sequence corrections and signal calibration
Background: The brightness of the probe spots on expression microarrays intends to measure the abundance of specific mRNA targets. Probes with runs of at least three guanines (G) ...
Mario Fasold, Peter F. Stadler, Hans Binder
BMCBI
2005
104views more  BMCBI 2005»
13 years 8 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...