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BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...
BIOCOMP
2006
13 years 8 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
COMPLIFE
2006
Springer
13 years 11 months ago
Relational Subgroup Discovery for Descriptive Analysis of Microarray Data
Abstract. This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to help find description of groups of genes different...
Igor Trajkovski, Filip Zelezný, Jakub Tolar...
DSS
2007
127views more  DSS 2007»
13 years 7 months ago
Large-scale regulatory network analysis from microarray data: modified Bayesian network learning and association rule mining
We present two algorithms for learning large-scale gene regulatory networks from microarray data: a modified informationtheory-based Bayesian network algorithm and a modified asso...
Zan Huang, Jiexun Li, Hua Su, George S. Watts, Hsi...