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» Inference of Sparse Networks with Unobserved Variables. Appl...
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BMCBI
2008
118views more  BMCBI 2008»
13 years 9 months ago
Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
Grace S. Shieh, Chung-Ming Chen, Ching-Yun Yu, Jui...
SDM
2007
SIAM
143views Data Mining» more  SDM 2007»
13 years 10 months ago
Less is More: Compact Matrix Decomposition for Large Sparse Graphs
Given a large sparse graph, how can we find patterns and anomalies? Several important applications can be modeled as large sparse graphs, e.g., network traffic monitoring, resea...
Jimeng Sun, Yinglian Xie, Hui Zhang, Christos Falo...
BMCBI
2005
178views more  BMCBI 2005»
13 years 8 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
13 years 10 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi