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BMCBI
2010
142views more  BMCBI 2010»
13 years 11 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
BMCBI
2008
156views more  BMCBI 2008»
13 years 11 months ago
The unique probe selector: a comprehensive web service for probe design and oligonucleotide arrays
Background: Nucleic acid hybridization, a fundamental technique in molecular biology, can be modified into very effective and sensitive methods for detecting particular targets mi...
Shu-Hwa Chen, Chen-Zen Lo, Ming-Chi Tsai, Chao A. ...
JASIS
2006
164views more  JASIS 2006»
13 years 11 months ago
A study of interface support mechanisms for interactive information retrieval
Advances in search technology have meant that search systems can now offer assistance to users beyond simply retrieving a set of documents. For example, search systems are now cap...
Ryen W. White, Ian Ruthven
BMCBI
2005
119views more  BMCBI 2005»
13 years 11 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2004
162views more  BMCBI 2004»
13 years 10 months ago
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant m
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...