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CIBCB
2005
IEEE
14 years 1 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...
BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2008
174views more  BMCBI 2008»
13 years 7 months ago
Evolutionary approaches for the reverse-engineering of gene regulatory networks: A study on a biologically realistic dataset
Background: Inferring gene regulatory networks from data requires the development of algorithms devoted to structure extraction. When only static data are available, gene interact...
Cédric Auliac, Vincent Frouin, Xavier Gidro...
BMCBI
2010
172views more  BMCBI 2010»
13 years 7 months ago
Inferring gene regression networks with model trees
Background: Novel strategies are required in order to handle the huge amount of data produced by microarray technologies. To infer gene regulatory networks, the first step is to f...
Isabel A. Nepomuceno-Chamorro, Jesús S. Agu...