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BMCBI
2008
166views more  BMCBI 2008»
13 years 7 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
BMCBI
2006
169views more  BMCBI 2006»
13 years 7 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2005
134views more  BMCBI 2005»
13 years 7 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
TNN
1998
114views more  TNN 1998»
13 years 7 months ago
Bayesian retrieval in associative memories with storage errors
Abstract—It is well known that for finite-sized networks, onestep retrieval in the autoassociative Willshaw net is a suboptimal way to extract the information stored in the syna...
Friedrich T. Sommer, Peter Dayan