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» Inferring differentiation pathways from gene expression
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BMCBI
2010
223views more  BMCBI 2010»
13 years 3 months ago
MetNetGE: interactive views of biological networks and ontologies
Background: Linking high-throughput experimental data with biological networks is a key step for understanding complex biological systems. Currently, visualization tools for large...
Ming Jia, Suh-Yeon Choi, Dirk Reiners, Eve Syrkin ...
BMCBI
2008
146views more  BMCBI 2008»
13 years 9 months ago
EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries
Background: Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as U...
Robin P. Smith, William J. Buchser, Marcus B. Lemm...
BICOB
2009
Springer
13 years 6 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...
BMCBI
2010
216views more  BMCBI 2010»
13 years 3 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
BMCBI
2010
148views more  BMCBI 2010»
13 years 9 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney