Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Self-adaptation of the mutation strengths is a powerful mechanism in evolution strategies (ES), but it can fail. As a consequence premature convergence or ending up in a local opt...
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...