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BIODATAMINING
2008
13 years 7 months ago
2008
During the past two decades, the field of human genetics has experienced an information explosion. The completion of the human genome project and the development of high throughpu...
BIOINFORMATICS
2008
13 years 7 months ago
2008
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
BMCBI
2010
13 years 7 months ago
2010
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
BMCBI
2010
13 years 7 months ago
2010
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
BMCBI
2010
13 years 7 months ago
2010
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...