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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2008
82views more  BMCBI 2008»
13 years 7 months ago
Envelope: interactive software for modeling and fitting complex isotope distributions
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
Michael T. Sykes, James R. Williamson
BMCBI
2006
106views more  BMCBI 2006»
13 years 7 months ago
Gene and protein nomenclature in public databases
Background: Frequently, several alternative names are in use for biological objects such as genes and proteins. Applications like manual literature search, automated text-mining, ...
Katrin Fundel, Ralf Zimmer
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
CAGD
2006
103views more  CAGD 2006»
13 years 7 months ago
The implicit structure of ridges of a smooth parametric surface
Given a smooth surface, a blue (red) ridge is a curve such that at each of its points, the maximum (minimum) principal curvature has an extremum along its curvature line. Ridges a...
Frédéric Cazals, Jean-Charles Faug&e...